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York at the forefront of trial for a new coronavirus vaccine

Thu 6 May, 2021 by YorkMix

A Pfizer-BioNTech vaccine is prepared at a vaccination centre in York. Danny Lawson / PA Wire

Filed Under: Health

York’s doctors, academics and volunteers are at the forefront of a trial for a new vaccine for Covid-19.

York and Scarborough Teaching Hospitals NHS Foundation Trust is to work with the University of York and Tees, Esk and Wear Valleys NHS Foundation Trust to trial the vaccine.

The study will involve a total of 30,000 adult subjects around the world. Locally about 150 people, aged between 18 and 40 who have not already had a vaccine for Covid-19, will take part in the trials.

York is one of nine locations across the UK taking part in the global trial and is a first for the city.

The trial, based at the University of York, will involve up to ten planned visits to the clinic over a two-year period, but this may be shorter depending upon the on-going results.

Lydia Harris, head of research and development at the York NHS Trust, said: “York is rapidly expanding its research capabilities.

“The quality of our researchers, facilities and patient groups are allowing us to engage effectively in cutting edge research at an international level. We have come a long way in a very short period of time.

“Our staff are doing incredible work to support Covid-19 research studies and we are very proud to have made significant contributions to this global effort.

“We’re really proud to be contributing to so many different studies for Covid-19.”

Exciting results

York Hospital. Photograph: Richard McDougall

Professor Charles Lacey from the Hull York Medical School is the principal investigator and will be leading the team.

Professor Lacey said: “Clinical studies are important for medical advances. Current available vaccines are only available because of research study volunteers.

“Although there are several approved Covid-19 vaccines available, research is ongoing to provide more options, since all vaccines may work differently in providing protection against Covid-19.

“The vaccine we are trialling showed very exciting results in phase 1/2 studies.”

Researchers will compare a placebo vaccine with the study vaccine, with participants crossing over during the trial and receiving both. Participants will not know when they are receiving the placebo or the investigational vaccine.


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